The Science Behind TargetCool

The Science Behind TargetCool

TargetCool-DEJ-Action

TargetCool Boosting specifically targets the dermal-epidermal junction (DEJ) to deliver benefits by promoting rapid absorption in both the epidermis and dermis. This reinforces skin layer connections and can potentially combat ageing effects like wrinkles and loss of elasticity, yielding quick results.

MTS + TargetCool

TargetCoolshowed a 252% increase in fluorescent intensity and a 37% increase in penetration depth compared to the negative control group. MTS + TargetCool showed the highest level of fluorescence intensity and penetration depth.

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Needleless Cooling Delivery System

The depth and the amount of solution injected during a skin booster procedure using a syringe may not be consistent, depending on the practitioner’s proficiency.
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The Boosting Mode ensures consistency, allowing for the absorption of the solution at a predetermined location. From the perspective of skin boosters, the boosting mode has a very good effect on absorbing the solution evenly over a large area.
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What is the DEJ?

The DEJ is the utmost upper part of the dermal layer that provides strong cohesion between the epidermis and the dermis, ultimately enhancing the skin’s resilience.

Distinct protein components in the DEJ include collagen, integrin, and laminin playing a vital role in maintaining integrity and functionality of the DEJ.
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Benefits of CO2 Cooling

1) Reduce inflammation: CO2regulates NF-kappa B, which induces the expression of genes that cause inflammation.

2) Improvement of blood circulation: CO2induces vasodilation, providing nutrients and oxygen to the skin tissue.

3) Oxygen supply: CO2 lowers blood pH and induces the Bohr effect to supply oxygen to cell tissues.

4) Formation of blood vessels: Increase vascular endothelial growth factor to form new blood

Before CO₂ spray detected After 1 minute of CO₂ spray detected After 2 minutes of CO₂ spray detected

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CO₂ detection in the epidermis CO₂ detection in the epidermis and upper dermis

Ultimately CO₂ diffuses and reaches the dermis with TargetCool